Tricarboxylic acids and derivatives
Medchemexpress LLC Magnesium citrate 100mg
Magnesium citrate (Trimagnesium dicitrate) is an orally active magnesium-containing compound that can cross the blood-brain barrier (BBB) Magnesium citrate can be used as an intestinal cleanser and is studied for its application in laxatives Magnesium citrate can also increase the pain threshold and is studied for pain-relief purposes[1][2]
Alkali Scientific Sodium Citrate, Trisodium Salt, Dihydrate, ACS Grade, 3 Kg
Sodium Citrate, Trisodium Salt, Dihydrate, ACS Grade, is a high-purity reagent used in laboratory applications, including buffer preparation and biochemical research. This 3 kg package ensures that researchers and laboratories have access to a reliable source of high-quality trisodium citrate for a variety of chemical and biological processes. The ACS-grade purity guarantees that the reagent meets the rigorous standards required for accurate and reproducible results. Sodium citrate is commonly used in the preparation of solutions for protein and enzyme assays, as well as for maintaining pH stability in a variety of applications including chromatography, electrophoresis, and molecular biology.
Medchemexpress LLC (Z)-aconitic acid | 585-84-2 | MFCD00063184 | 99.3% | 174.11 g/mol | C6H6O6 | 5 MG
(Z)-aconitic acid is a small-molecule endogenous metabolite (cis-aconitic acid) reported to act as a glutamate decarboxylase inhibitor with activity that includes reduction of IκB-α phosphorylation and inhibition of inflammatory responses; supplied as a solid for research use.
- Molecular formula C6H6O6 and molecular weight 174.11 g/mol.
- High reported purity (99.28%).
- Reported activity as a glutamate decarboxylase inhibitor and modulator of IκB-α phosphorylation.
- Applicable to research on inflammatory and metabolic pathways.
- Powder stability: -20°C for long-term storage; defined solvent storage conditions available.
Medchemexpress LLC Fmoc-NH-PEG6-CH2COOH | 437655-96-4 | 99.2% | 10 G
Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). This compound also functions as a PEG-based PROTAC linker for the synthesis of PROTACs, which exploit the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Cleavable ADC linker
- PEG-based PROTAC linker
- Used in the synthesis of antibody-drug conjugates
- Used in the synthesis of PROTACs
- Molecular formula: C29H39NO10
- Molecular weight: 561.62
- Soluble in DMSO at 100 mg/mL (178.06 mM); requires ultrasonic
![Alkali Scientific 4 Methylumbelliferyl B D glucopyranoside Monohydrate [Methylumbelliferyl B D glucoside], 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659985.jpg-250.jpg)
Alkali Scientific 4 Methylumbelliferyl B D glucopyranoside Monohydrate [Methylumbelliferyl B D glucoside], 1 G
Methylumbelliferyl β-D Glucopyranoside Monohydrate, 1 g is a high-purity reagent used in biochemical analysis to study glucosidase enzyme activity. When cleaved by glucosidases, this substrate releases a fluorescent product, which can be measured in enzyme assays. This property makes it essential in the study of enzyme kinetics and metabolic processes. It is frequently used in laboratory research for microbial assays, diagnostic testing, and in studying enzymatic reactions in various biological systems. The high purity and sensitivity of this reagent ensure reliable and reproducible results in applications that require precise enzyme activity detection.
Medchemexpress LLC Citrate Synthetase Antibody (YA2802) | 10 UL
Citrate Synthetase Antibody (YA2802) is a rabbit-derived, non-conjugated IgG monoclonal antibody. It targets Citrate Synthetase and is suitable for various antibody-related applications.
- Rabbit-derived
- Non-conjugated IgG monoclonal antibody
- Targets Citrate Synthetase
- Recombinant antibody
- Predicted band size: 52 kDa
- Observed band size: 45 kDa
Medchemexpress LLC 2-methylcitric acid trisodium | 117041-96-0 | MFCD16875437 | 96.0% | 272.10 g·mol⁻1 | C7H7Na3O7 | 5 MG
2-Methylcitric acid trisodium is the trisodium salt of 2-methylcitric acid provided as a white to off-white solid for laboratory research. It is an endogenous metabolite used as a marker in methylmalonic and propionic acidemias and is employed in biochemical and mitochondrial studies, where it has been reported to inhibit ADP-stimulated mitochondrial respiration supported by glutamate.
- Trisodium salt, white to off-white solid.
- CAS number 117041-96-0.
- Purity 96.0%.
- Molecular weight 272.10 g·mol⁻1; formula C7H7Na3O7.
- Highly soluble in water (100 mg/mL; may require ultrasonication).
- Storage: sealed at 4°C; in solvent -80°C (6 months), -20°C (1 month).
- For research use only; not for human or veterinary use.
Medchemexpress LLC cGAMP diammonium | 96.6% | 708.47 | 50 MG
cGAMP (Cyclic GMP-AMP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. It activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators.
- Endogenous second messenger in metazoans.
- Triggers interferon production in response to cytosolic DNA.
- Activates stimulator of interferon genes (STING).
- Activates a signaling cascade leading to the production of type I interferons and other immune mediators.
- Promotes the antigen-specific proliferation capacity of spleen cells in mice.
- Directly activates murine and human dendritic cells *in vitro*.
Apexbio Technology LLC Clomiphene citrate 50-41-9 10mM (in 1mL DMSO)
Clomiphene citrate (CAS 50-41-9) is a small-molecule modulator targeting estrogen receptors (ER) It is designed to selectively modulate ER-mediated signaling thereby influencing estrogen-dependent cellular pathways Clomiphene citrate exerts its biological activity primarily through competitive inhibition at estrogen receptors It demonstrates both antiestrogenic and estrogenic activities depending on tissue context Based on these pharmacological properties clomiphene citrate holds research potential in the investigation of estrogen receptor-mediated transcriptional regulation cellular proliferation and differentiation as well as hypothalamic-pituitary-gonadal axis regulation and ovarian follicular maturation in reproductive biology studies
Medchemexpress LLC DiMal-O-CH2COOH | 1620837-47-9 | 96.8% | 308.24 | C13H12N2O7 | 10 MG
This cleavable linker is designed for use in antibody-drug conjugate (ADC) construction and conjugation workflows, offering malemide-based chemistry for attaching payloads to antibodies or targeting moieties. It is provided at research-grade purity and supplied in small quantities suitable for method development and exploratory studies.
- Cleavable linker for ADC construction and conjugation workflows.
- Provides maleimide-based chemistry for reliable payload attachment.
- High purity (96.8%) suitable for research applications.
- Available in small research quantities; larger amounts available on request.
- Store at 4°C, protect from light; in solvent: -80°C (6 months) or -20°C (1 month).
Medchemexpress LLC Tamoxifen (Citrate) | 54965-24-1 | 99.9% | 563.64 | 1 ML
Tamoxifen Citrate is an orally active, selective estrogen receptor modulator (SERM) that blocks estrogen action in breast cells while activating estrogen activity in other cells like bone, liver, and uterine cells. It functions as a potent Hsp90 activator, enhancing its molecular chaperone ATPase activity. Additionally, it can inhibit infectious EBOV Zaire and Marburg (MARV).
- Selective estrogen receptor modulator
- Blocks estrogen action in breast cells
- Activates estrogen activity in bone, liver, and uterine cells
- Potent Hsp90 activator
- Enhances Hsp90 molecular chaperone ATPase activity
- Inhibits infectious EBOV Zaire and Marburg (MARV)
- Activates autophagy
- Induces apoptosis
- Used to induce gene knockout in CreER transgenic mice
Medchemexpress LLC m-PEG8-CH2COOH | 102013-72-9 | 99.9% | 5 G
m-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It has a molecular weight of 442.50 and a chemical formula of C19H38O11. This compound appears as a colorless to light yellow liquid with a density of 1.122 g/cm3. For in vitro solubility, it dissolves in DMSO at 200 mg/mL.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Molecular weight: 442.50
- Formula: C19H38O11
- Appearance: liquid
- Color: colorless to light yellow
- In vitro solubility: 200 mg/mL in DMSO
- Pure form storage: stable for 3 years at -20°C or 2 years at 4°C
- In solvent storage: stable for 6 months at -80°C or 1 month at -20°C
Medchemexpress LLC Cyclic GMP-AMP diammonium | 96.6% | 708.47 g/mol | C20H30N12O13P2 | 5 MG
cGAMP diammonium is a cyclic dinucleotide that functions as an endogenous second messenger and a potent activator of the stimulator of interferon genes (STING) pathway. Provided as the diammonium salt for research use, it induces type I interferon production and is used to study innate immune signaling.
- Activates STING and triggers type I interferon signaling.
- High purity (96.6%) suitable for research applications.
- Molecular formula C20H30N12O13P2; molecular weight 708.47 g/mol.
- Water-soluble; dissolves up to 100 mg/mL with ultrasonic assistance.
- Solid storage recommended at -20°C; solution storage guidance provided.
- Supplied in small quantities (e.g., 5 mg) for laboratory use.
Medchemexpress LLC ζ-Stat trisodium (NSC37044 trisodium) | 31894-34-5 | 97.0% | 450.31 | C10H5Na3O10S3 | 50MG
ζ-Stat trisodium is a small-molecule inhibitor of protein kinase C zeta (PKC-ζ) used in biochemical and cellular research. It is supplied as a light yellow to light brown solid with a reported purity of 97.0%, molecular formula C10H5Na3O10S3, and molecular weight 450.31 g/mol. The compound is typically provided in small, preweighed quantities suitable for laboratory studies.
- Inhibits protein kinase C zeta (PKC-ζ) activity.
- CAS number 31894-34-5.
- Purity 97.0%.
- Molecular formula C10H5Na3O10S3; molecular weight 450.31 g/mol.
- Solid, light yellow to light brown appearance.
- Available in multiple small research quantities (mg scale).
![Medchemexpress LLC Methyl 2-[(4-chlorobenzoyl)amino]-4-ethyl-5-methylthiophene-3-carboxylate | 544450-68-2 | 99.9% | C16H16ClNO3S | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000260202.png-250.jpg)
Medchemexpress LLC Methyl 2-[(4-chlorobenzoyl)amino]-4-ethyl-5-methylthiophene-3-carboxylate | 544450-68-2 | 99.9% | C16H16ClNO3S | 10MG
COR659 (methyl 2-[(4-chlorobenzoyl)amino]-4-ethyl-5-methylthiophene-3-carboxylate; CAS 544450-68-2) is a small-molecule positive allosteric modulator of the GABAB receptor used in preclinical neuroscience and addiction research. It has been reported to reduce alcohol- and chocolate-seeking behavior in rodent models and is supplied as a high-purity research chemical for in vitro and in vivo pharmacology studies.
- Potent GABAB positive allosteric modulator with demonstrated in vivo activity.
- High purity suitable for research applications.
- Well characterized chemical identifiers and molecular formula.
- Off-white solid form compatible with standard solvents such as DMSO.
- Storage and handling guidance provided for refrigerated and cryogenic conditions.