Tricarboxylic acids and derivatives
Medchemexpress LLC Adenosine 5'-(α,β-methylene)diphosphate triammonium | 00-00-0 | MFCD00042991 | 99.9% | 476.32 g·mol⁻¹ | C11H26N8O9P2 | 5 MG
MethADP triammonium (Adenosine 5'-(α,β-methylene)diphosphate triammonium) is a nucleotide analog used as a selective CD73 inhibitor for research into the ATP-adenosine pathway. Supplied as the triammonium salt, it is provided for laboratory research use in solid or solution form.
- CD73 inhibitor for ATP-adenosine pathway studies.
- High purity: 99.9%.
- Molecular weight 476.32 g·mol⁻¹; chemical formula C11H26N8O9P2.
- Appearance: off-white to light yellow solid.
- Storage: solid at 4°C; in solvent -80°C up to 6 months, -20°C up to 1 month.
- Available in small solid quantities and as a 10 mM solution.
Apexbio Technology LLC Mosapride Citrate 112885-42-4 10mM (in 1mL DMSO)
Mosapride Citrate (CAS 112885-42-4) is a small molecule that functions as a selective agonist of the 5-hydroxytryptamine 4 (5-HT ) receptor and an antagonist of the 5-HT receptor with negligible activity at dopaminergic D adrenergic and as well as 5-HT and 5-HT receptors By modulating serotonin receptor activity it enhances gastrointestinal motility and accelerates gastric emptying Mosapride Citrate is widely used in research investigating serotonergic signaling pathways gut motility regulation and potential therapeutic approaches for gastrointestinal disorders
Apexbio Technology LLC Pentoxyverine Citrate 23142-01-0 10mM (in 1mL DMSO)
Pentoxyverine Citrate (CAS 23142-01-0) is a small-molecule antagonist targeting acetylcholine receptors (AChR) including 1 and 2 receptors It acts by inhibiting central and peripheral cholinergic pathways thereby regulating neural control of cough reflex sensitivity Pentoxyverine Citrate exerts its biological activity primarily through suppression of the cough reflex via modulation of sensory nerve pathways It demonstrates antitussive anticonvulsant and antispasmodic activity with K i values of 41 nM for 1 894 nM for 2 and 75 nM for 1 receptors in guinea pig brain membrane models Based on these pharmacological properties Pentoxyverine Citrate holds research potential in studies of cough physiology cholinergic neurotransmission and therapeutic interventions in respiratory conditions
![Medchemexpress LLC Acetic acid, 2-[2-(2-azidoethoxy)ethoxy]- | 882518-90-3 | 99.0% | 189.17 | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Acetic acid, 2-[2-(2-azidoethoxy)ethoxy]- | 882518-90-3 | 99.0% | 189.17 | 1 MG
Azido-PEG2-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Can be used in the synthesis of PROTACs
- PROTACs utilize the intracellular ubiquitin-proteasome system to degrade target proteins
Medchemexpress LLC Acetic acid, 2-[2-(2-azidoethoxy)ethoxy]- | 882518-90-3 | 99.03% | 189.17 | 10 MG
Azido-PEG2-CH2COOH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It also functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Can be used in the synthesis of PROTACs.
- Functions as a click chemistry reagent.
- Azide group enables copper-catalyzed azide-alkyne cycloaddition.
- Can undergo strain-promoted alkyne-azide cycloaddition with DBCO or BCN groups.
Sigma Aldrich Fine Chemicals Biosciences Ammonium citrate dibasic BioXtra, >=99.0% (T) | 3012-65-5 | MFCD00013068 | 500G
Ammonium citrate dibasic BioXtra, >=99.0% (T) | Purity: >=99.0% (T) | Mol Wt: 226.18 | 3012-65-5 | MFCD00013068 | 500G
Apexbio Technology LLC Orphenadrine Citrate 4682-36-4 10mM (in 1mL DMSO)
Orphenadrine Citrate (CAS 4682-36-4) is a small molecule utilized in biomedical research for its pharmacological modulation of neurological pathways It acts by inhibiting the binding of [ 3H]MK-801 to the phencyclidine (PCP) site of the N-methyl-D-aspartate (NMDA) receptor in human frontal cortex tissue implicating antagonism at NMDA-type glutamate receptors Orphenadrine has historically served as an antiparkinsonian antispastic and analgesic agent Its ability to modulate NMDA receptor activity makes it a valuable tool for studies investigating glutamatergic neurotransmission and related neuropharmacological mechanisms
Medchemexpress LLC 5,8,11,14,17,20-hexaoxa-2-azadocosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester | 437655-96-4 | MFCD26142983 | 99.4% | 561.62 g/mol | C29H39NO10 | 50 MG
Fmoc-NH-PEG6-CH2COOH is an Fmoc-protected PEG6 linker bearing a terminal carboxylic acid and an Fmoc-protected amine. It is used as a hydrophilic spacer in the synthesis of proteolysis targeting chimeras (PROTACs) and antibody-drug conjugates (ADCs), providing solubility and a reactive handle for amide coupling.
- Fmoc-protected amine for orthogonal protection in synthesis.
- Terminal carboxylic acid suitable for amide coupling.
- PEG6 spacer increases hydrophilicity and solubility.
- High reported purity (≈99.4%).
- Available in multiple package sizes for milligram to gram scale work.
Medchemexpress LLC Azido-PEG2-CH2COOH | 882518-90-3 | 99.03% | 189.17 | 1 ML
Azido-PEG2-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is a click chemistry reagent containing an Azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs use the intracellular ubiquitin-proteasome system to degrade target proteins.
- PEG-based PROTAC linker.
- Click chemistry reagent.
- Contains an Azide group for CuAAc reaction with Alkyne groups.
- Can undergo SPAAC reactions with DBCO or BCN groups.
eMolecules 1204918-73-9 | Medchem Express | (E/Z)-Zotiraciclib (citrate) | 5mg | 716993856 | HY-15166B | 564.595 | C29H32N4O8
Ambeed | 4-Pyrrolidin-2-ylpyridine | 250mg | 552520275 | A104385 | 128562-25-4 | MFCD01862536 | 148.209 | C9H12N2
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Selleck Chemical LLC Tamoxifen Citrate S1972-1g
Tamoxifen Citrate is a selective estrogen receptor modulator (SERM) Tamoxifen Citrate is also a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity Tamoxifen induces apoptosis and autophagy
Accela Chembio Inc Tri-o-acetyl-d-glucal | 25g | 2873-29-2 | MFCD00063253 | 97+% | Shelf Life: 720 Days | Light Sensitive
Tri-o-acetyl-d-glucal | 25g | 2873-29-2 | MFCD00063253 | 97+% | Shelf Life: 720 Days | Light Sensitive
Chemscene ChemScene | Tris(4-(trifluoromethyl)phenyl)phosphine | 25G | CS-W011542 | 0.98 | 13406-29-6| MFCD00058883 | 466.28
ChemScene | Tris(4-(trifluoromethyl)phenyl)phosphine | 25G | CS-W011542 | 0.98 | 13406-29-6| MFCD00058883 | 466.28
Medchemexpress LLC Sparfosic acid trisodium | 70962-66-2 | MFCD32693867 | 98.0% | 321.06 g/mol | C6H7NNa3O8P | 5 MG
Sparfosic acid trisodium (CAS 70962-66-2) is a research-grade DNA antimetabolite that potently inhibits aspartate transcarbamoyl transferase (ATCase). Supplied as the trisodium salt, it is used in biochemical and cell-based studies to probe pyrimidine biosynthesis and to assess synergistic cytotoxic effects in combination with chemotherapeutic agents.
- Potent ATCase inhibitor for studying pyrimidine biosynthesis.
- 98.0% purity suitable for research applications.
- Supplied as the trisodium salt in solid powder form.
- Available in small pack sizes (5 mg-100 mg) and as 10 mM in DMSO solution.
- Molecular weight 321.06 g/mol; formula C6H7NNa3O8P.
- Useful in cell-based assays to evaluate synergy with chemotherapeutics.
Medchemexpress LLC CH2COOH-PEG3-CH2COOH | 32775-08-9 | 99.1% | 5 G
CH2COOH-PEG3-CH2COOH is a PEG-based linker bearing two terminal carboxylic acid groups used as a building block in the chemical synthesis of Proteolysis Targeting Chimeras (PROTACs) and other conjugates for research.
- Provides two terminal carboxylic acids for covalent or amide coupling
- Peg3 spacer enhances solubility and flexibility in conjugates
- High listed purity suitable for research use
- Molecular weight 266.25; chemical formula C10H18O8
- Available in small-scale packages for synthetic work